Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity related to bortezomib, a proteasome inhibitor used in the treatment of several myeloma. Its synthesis or study is vital for making sure the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the treatment method of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-one): A key compound inside the synthesis of imatinib, a drug that targets particular kinds of cancer, which includes chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers including breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates while in the synthesis of gemcitabine, an anti-cancer drug. Their study is essential for optimizing the production process and making sure high purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is used to treat breast cancer, and these intermediates are linked to its generation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist Utilized in the therapy of breast cancer. Several intermediates assist in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug successful in managing cancers which include ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most 5 cancers and tiny cell lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, that have different purposes, which includes antiviral properties.
Vildagliptin Intermediates: Employed in the creation CAS NO. 302964-08-5 of vildagliptin, an oral drug for style 2 diabetic issues that inhibits the enzyme DPP-four to control blood sugar ranges.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is linked to the synthesis of various gluconic acid derivatives, that happen to be Employed in food items, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor from the synthesis of canagliflozin, a medication made use of to deal with form 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).